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PROTECTIVE GROUPS IN ORGANIC SYNTHESIS
J. F. W. McOmie (Ed., Protective Groups In Organic Chemistry, Plenum Press, New York And London, 1973) For His Interest In The Project And For Several Exchanges Of Correspondence, And To Mrs. Mary Fieser, Professor Frederick D. Greene, And Ix . X PREFACE Jul 2th, 2024

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PROTECTING GROUPS IN ORGANIC SYNTHESIS
Protecting Groups: A Necessary Evil 3 Note, However, That Each Protecting Group Incorporated In A Multi-step Synthesis Increases The Synthesis By Two Non-productive Steps Re Feb 3th, 2024

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Lewis Acid: S N1 Mechanism Na/NH 3 O R_ HO R 2e-, H+ CrO 3: Via Benzoate O R O R HO CrO R 3-OH O Allyl Ether On: Usually Allyl Br/Cl + Base. Usually Easy O O OH HO HO OH HO O O Ph Bu 2SnO O O OH HO O O O O Ph Bu Sn Bu "stanylene Acetal" Br O O OH HO O OH HO O O Ph 95% Ogawa, TL, 1988, 409 Mar 3th, 2024

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• A Study Comparing Alkoxysilyl Vs. Trialkylsilyl Groups Has Also Been Done: P. Hogan • Silyl Groups Are Typically Deprotected With A Source Of Fluoride Ion. The Si–F Bond Stength Is About 30 Kcal/mol Stronger Than The Si–O Bond. Fluoride Sources: Tetrabutylammonium Mar 2th, 2024

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